After defeating the villains at the Flood Zone, Izuku, Minoru and Tsuyu successfully escape the Flood Zone. Tsuyu wonders what their next course of action should be with Izuku suggesting that they should try and call for help. Tsuyu then notes that their teacher Shota is fighting a large group of villains in the Central Plaza. Izuku then says that they should watch their teacher battling and when there are openings, they should jump in and help in order to relieve their teacher's burden.
At the Landslide Zone, Shoto Todoroki easily defeats the villains there by freezing them all.
At the Mountain Zone, Denki, Momo and Kyoka battle the villains there. Momo creates an insulator sheet to protect herself and Kyoka, allowing Denki to discharge a great amount of electricity, which electrocutes all the villains, defeating them.
At the Central Plaza, Shota continues fighting the villains and finally faces the ringleader, Tomura Shigaraki. Shota manages to strike Tomura, but Tomura grabs Shota's elbow and starts disintegrating it. Shota punches Tomura and knocks him down, then defeats two villains to attempted to attack him. Suddenly, a monstrous villain appears behind Shota.
Near the exit of the U.S.J, Kurogiri and Thirteen battle. However, Kurogiri defeats Thirteen by warping Thirteen's Quirk against herself, causing Thirteen to start turning to dust, which incapacitates Thirteen. Tenya begins running towards the exit with Kurogiri in pursuit. As Kurogiri appears before Tenya, Mezo jumps into Kurogiri, stopping Kurogiri and allowing Tenya to continue running towards the exit.
Izuku, Tsuyu and Minoru reach the Central Plaza but are shocked to see that their teacher Shota is severely wounded and on the ground due to being defeated by the monstrous villain. Tomura asks the Heroes to tell All Might that he is wanted by Artificial Human "Nomu".